English
1-Hydroxybenzotriazole hydrate (HOBt)
Phân loại: Reagent
Thương hiệu: DEAJUNG
:
| CAS Number | 123333-53-9 |
|---|---|
| Linear Formula | C6H5N3O · nH2O |
| Molecular Weight | 135.12(anh.) |
| Syhonym | HOBT |
| Maker | DAEJUNG |
| Catalog Number | 4112-4405 |
| Assay | 98% |
| Grade | EP |
| Package | 500G |
| mp(Melting Point) | 155~158°C |
CHI TIẾT :
DESCRIPTION
General description
1-Hydroxybenzotriazole is a coupling reagent used to synthesize amides by the condensation reaction between the activated ester/acid and the amino group of protected amino acids. It is also used as a racemization suppressor during peptide synthesis.
Application
1-Hydroxybenzotriazole hydrate can be used as a condensation reagent to prepare:
- Poly-γ-glutamic acid methyl ester from a dimer of γ-glutamic acid.
- Oxadiazoles via cyclo condensation of amidoximes with trifluoroacetic anhydride or benzoic acid derivatives.